BDBM50464891 CHEMBL4286717

SMILES CCC1(C)CC(=O)N(CCCCN2CCN(CC2)c2cccc3sccc23)C(=O)C1

InChI Key InChIKey=MCWADYMQWQHSRA-UHFFFAOYSA-N

Data  7 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50464891   

TargetMuscarinic acetylcholine receptor M3(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50464891(CHEMBL4286717)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at M3 receptor (unknown origin) after 10 mins by calcium 5 dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50464891(CHEMBL4286717)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at dopamine D2 receptor (unknown origin) after 60 mins by Ultra lance cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50464891(CHEMBL4286717)
Affinity DataIC50: 606nMAssay Description:Antagonist activity at 5-HT2C receptor (unknown origin) after 10 mins by calcium 5 dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50464891(CHEMBL4286717)
Affinity DataIC50: 253nMAssay Description:Antagonist activity at histamine H1 receptor (unknown origin) after 10 mins by calcium 5 dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50464891(CHEMBL4286717)
Affinity DataIC50: 6.21E+3nMAssay Description:Inhibition of human ERG by auomated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50464891(CHEMBL4286717)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) after 10 mins by calcium 5 dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50464891(CHEMBL4286717)
Affinity DataIC50: 376nMAssay Description:Antagonist activity at adrenergic alpha1A receptor (unknown origin) after 10 mins by calcium 5 dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50464891(CHEMBL4286717)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at 5-HT1A receptor (unknown origin) after 60 mins by Ultra lance cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed