BDBM50448145 CHEMBL3122206

SMILES CCN(CC)C(=O)c1nn(C)c2nc(OCc3ccccn3)cnc12

InChI Key InChIKey=FTDUCDNGVCWREJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448145   

TargetMetabotropic glutamate receptor 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50448145(CHEMBL3122206)
Affinity DataIC50: 5.00E+4nMAssay Description:Negative allosteric modulation of human mGluR1 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium flux after 16 to 24 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50448145(CHEMBL3122206)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]-MPEPy from human mGluR5 expressed in HEK293FT cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed