BDBM50446564 CHEMBL3109404

SMILES COC(=O)c1cc(O)c(O)c(C[C@]2(C)[C@@H](C)CC[C@]3(C)[C@H]2CCC=C3C)c1

InChI Key InChIKey=VXQUGYOYJDITTO-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50446564   

TargetSerine/threonine-protein kinase N1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50446564(CHEMBL3109404)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant PRK1 (unknown origin) using casein as substrate assessed as incorporation of [gamma-33P]-ATP into substrate by radiometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50446564(CHEMBL3109404)
Affinity DataIC50: 2.17E+4nMAssay Description:Inhibition of recombinant PLK1 (unknown origin) using casein as substrate assessed as incorporation of [gamma-33P]-ATP into substrate by radiometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50446564(CHEMBL3109404)
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) assessed as incorporation of [gamma-33P]-ATP into substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek6(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50446564(CHEMBL3109404)
Affinity DataIC50: 7.72E+3nMAssay Description:Inhibition of recombinant NEK6 (unknown origin) assessed as incorporation of [gamma-33P]-ATP into substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50446564(CHEMBL3109404)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of recombinant NEK2 (unknown origin) assessed as incorporation of [gamma-33P]-ATP into substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50446564(CHEMBL3109404)
Affinity DataIC50: 3.12E+3nMAssay Description:Inhibition of wild type MET (unknown origin) assessed as incorporation of [gamma-33P]-ATP into substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50446564(CHEMBL3109404)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of recombinant IGF1R (unknown origin) using Poly (Glu,Tyr) 4:1 as substrate assessed as incorporation of [gamma-33P]-ATP into substrate by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50446564(CHEMBL3109404)
Affinity DataIC50: 4.56E+3nMAssay Description:Inhibition of recombinant FAK (unknown origin) assessed as incorporation of [gamma-33P]-ATP into substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50446564(CHEMBL3109404)
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of recombinant AXL (unknown origin) assessed as incorporation of [gamma-33P]-ATP into substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50446564(CHEMBL3109404)
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of recombinant aurora kinase B (unknown origin) using tetra(LRRWSLG) as substrate assessed as incorporation of [gamma-33P]-ATP into substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNUAK family SNF1-like kinase 1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50446564(CHEMBL3109404)
Affinity DataIC50: 2.94E+4nMAssay Description:Inhibition of recombinant ARK5 (unknown origin) assessed as incorporation of [gamma-33P]-ATP into substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50446564(CHEMBL3109404)
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of recombinant ALK (unknown origin) assessed as incorporation of [gamma-33P]-ATP into substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50446564(CHEMBL3109404)
Affinity DataIC50: 4.84E+4nMAssay Description:Inhibition of recombinant AKT1 (unknown origin) using GSK3 (14 to 27) as substrate assessed as incorporation of [gamma-33P]-ATP into substrate by rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed