BDBM50444559 CHEMBL3099690

SMILES COc1cc(ccc1[C@]1(CCc2cncn12)C(=O)N(C)Cc1ccc(F)cc1)C#N

InChI Key InChIKey=LFTGJUPXDYIBLS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50444559   

TargetCytochrome P450 11B2, mitochondrial(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50444559(CHEMBL3099690)
Affinity DataIC50: 5nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed