BDBM50444409 CHEMBL3091581

SMILES OC(=O)c1ccc(NC(=O)[C@H](CC2CCCC2)n2cnc(c2)S(=O)(=O)C2CCC2)nc1

InChI Key InChIKey=DTZWAELYQGJRJI-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50444409   

TargetHexokinase-4(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50444409(CHEMBL3091581)
Affinity DataEC50:  1.74E+5nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as glucose-stimulated insulin secretionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50444409(CHEMBL3091581)
Affinity DataEC50:  201nMAssay Description:Activation of recombinant human glucokinase by G6PDH/NADP coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetHexokinase-4(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50444409(CHEMBL3091581)
Affinity DataIC50: 1.70E+3nMAssay Description:Activation of glucokinase in Wistar rat hepatocytes assessed as nuclear to cytosolic translocation of protein by immunofluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed