BDBM50435509 CHEMBL2392498

SMILES N[C@H]1CC[C@@H](CC1)n1nnc2cnc3[nH]ccc3c12

InChI Key InChIKey=BOSVNYKKFYBKJG-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50435509   

TargetTyrosine-protein kinase JAK1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50435509(CHEMBL2392498)
Affinity DataEC50:  729nMAssay Description:Inhibition of JAK1-mediated STAT3 phosphorylation in IL6-induced human TF1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50435509(CHEMBL2392498)
Affinity DataKi:  21nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50435509(CHEMBL2392498)
Affinity DataKi:  121nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed