BDBM50390994 CHEMBL1743263

SMILES CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@@H]3C[C@H]4[C@@H](Cc5c[nH]c6cccc4c56)N(C)C3)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C

InChI Key InChIKey=PBUNVLRHZGSROC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50390994   

TargetATP-dependent translocase ABCB1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50390994(CHEMBL1743263)
Affinity DataKi:  1.98E+4nMAssay Description:TP_TRANSPORTER: increase in Vinblastine intracellular accumulation in MDR1-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50390994(CHEMBL1743263)
Affinity DataKi:  3.61E+5nMAssay Description:TP_TRANSPORTER: increase in Calcein-AM intracellular accumulation in MDR1-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50390994(CHEMBL1743263)
Affinity DataKi:  1.60E+5nMAssay Description:TP_TRANSPORTER: increase in Calcein-AM intracellular accumulation in mdr1b-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50390994(CHEMBL1743263)
Affinity DataKi:  3.33E+5nMAssay Description:TP_TRANSPORTER: increase in Calcein-AM intracellular accumulation in mdr1a-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed