BDBM50387125 4-ureidophenyl sulfamate ring derivative 3j::CHEMBL2047805

SMILES NS(=O)(=O)Oc1ccc(NC(=O)Nc2c(F)c(F)c(F)c(F)c2F)cc1

InChI Key InChIKey=OHYPSOMCJGAUFK-UHFFFAOYSA-N

Data  13 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50387125   

TargetCarbonic anhydrase 12(Human)
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387125(CHEMBL2047805 | 4-ureidophenyl sulfamate ring deri...)
Affinity DataKi:  1nMAssay Description:Inhibition of human carbonic anhydrase-12More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387125(CHEMBL2047805 | 4-ureidophenyl sulfamate ring deri...)
Affinity DataKi:  1nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387125(CHEMBL2047805 | 4-ureidophenyl sulfamate ring deri...)
Affinity DataKi:  1nMAssay Description:Inhibition of human recombinant transmembrane CA12 preincubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387125(CHEMBL2047805 | 4-ureidophenyl sulfamate ring deri...)
Affinity DataKi:  5nMAssay Description:Inhibition of human carbonic anhydrase-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387125(CHEMBL2047805 | 4-ureidophenyl sulfamate ring deri...)
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387125(CHEMBL2047805 | 4-ureidophenyl sulfamate ring deri...)
Affinity DataKi:  6nMAssay Description:Inhibition of human carbonic anhydrase 9 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387125(CHEMBL2047805 | 4-ureidophenyl sulfamate ring deri...)
Affinity DataKi:  6nMAssay Description:Inhibition of human recombinant transmembrane CA9 preincubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387125(CHEMBL2047805 | 4-ureidophenyl sulfamate ring deri...)
Affinity DataKi:  136nMAssay Description:Inhibition of human carbonic anhydrase-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387125(CHEMBL2047805 | 4-ureidophenyl sulfamate ring deri...)
Affinity DataKi:  145nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387125(CHEMBL2047805 | 4-ureidophenyl sulfamate ring deri...)
Affinity DataKi:  145nMAssay Description:Inhibition of human recombinant cytosolic CA2 preincubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50387125(CHEMBL2047805 | 4-ureidophenyl sulfamate ring deri...)
Affinity DataKi:  3.18E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50387125(CHEMBL2047805 | 4-ureidophenyl sulfamate ring deri...)
Affinity DataKi:  3.18E+3nMAssay Description:Inhibition of human recombinant cytosolic CA1 preincubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50387125(CHEMBL2047805 | 4-ureidophenyl sulfamate ring deri...)
Affinity DataKi:  3.42E+3nMAssay Description:Inhibition of human carbonic anhydrase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed