BDBM50386715 CHEMBL2048917

SMILES COc1ccc(cc1OC)CCNC(=O)c2ccc(cc2)S(=O)(=O)N

InChI Key InChIKey=ZVVZHSQXKXOTQG-UHFFFAOYSA-N

Data  5 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50386715   

TargetCarbonic anhydrase 2(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50386715(CHEMBL2048917)
Affinity DataKi:  2.70nMAssay Description:Inhibition of human recombinant full length CA2-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50386715(CHEMBL2048917)
Affinity DataKi:  3.80nMAssay Description:Inhibition of human recombinant CA9 catalytic domain-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50386715(CHEMBL2048917)
Affinity DataKi:  4.30nMAssay Description:Inhibition of human recombinant full length CA14-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50386715(CHEMBL2048917)
Affinity DataKi:  5.80nMAssay Description:Inhibition of human recombinant full length CA7-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50386715(CHEMBL2048917)
Affinity DataKi:  8.70nMAssay Description:Inhibition of human recombinant full length CA1-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed