BDBM50379246 CHEMBL2011481

SMILES OCC(CO)OC(=O)CCCCCc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=ZDLSZSPJHZXEHK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50379246   

TargetMonoglyceride lipase(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379246(CHEMBL2011481)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379246(CHEMBL2011481)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379246(CHEMBL2011481)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379246(CHEMBL2011481)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of rat brain membrane FAAH assessed as [3H]-anandamide hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379246(CHEMBL2011481)
Affinity DataIC50: 7.59E+3nMAssay Description:Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379246(CHEMBL2011481)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of rat brain membrane FAAH assessed as [3H]-anandamide hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed