BDBM50309930 6-((1S,7R,10S,13R)-2,8,11,25-Tetraoxo-3,9,12,24-tetraaza-tricyclo[11.10.2.0*3,7*]pentacos-10-yl)-hexanoic acid hydroxyamide::CHEMBL592719

SMILES ONC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@@H]2CCCCCCCCCC[C@@H](NC1=O)C(=O)N2

InChI Key InChIKey=BVYNKHHGAJSMBT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50309930   

TargetHistone deacetylase 1(Human)
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309930(6-((1S,7R,10S,13R)-2,8,11,25-Tetraoxo-3,9,12,24-te...)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309930(6-((1S,7R,10S,13R)-2,8,11,25-Tetraoxo-3,9,12,24-te...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309930(6-((1S,7R,10S,13R)-2,8,11,25-Tetraoxo-3,9,12,24-te...)
Affinity DataIC50: 410nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309930(6-((1S,7R,10S,13R)-2,8,11,25-Tetraoxo-3,9,12,24-te...)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309930(6-((1S,7R,10S,13R)-2,8,11,25-Tetraoxo-3,9,12,24-te...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of HDAC4More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Graduate School of Life Science and Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50309930(6-((1S,7R,10S,13R)-2,8,11,25-Tetraoxo-3,9,12,24-te...)
Affinity DataIC50: 410nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed