BDBM50306239 4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-(1-(cyclopropanecarbonyl)piperidin-4-yl)-1H-pyrazole-3-carboxamide::CHEMBL594280

SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)NC1CCN(CC1)C(=O)C1CC1

InChI Key InChIKey=BIEMFEVSMALXHH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306239   

TargetCannabinoid receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50306239(4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...)
Affinity DataIC50: 1.20nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50306239(4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...)
Affinity DataIC50: 3.70nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed