BDBM50294034 (R,S)-2-(3,3-Diethylthioureido)-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic Acid::CHEMBL551696

SMILES CCN(CC)C(=S)Nc1sc2CCCC(C)c2c1C(O)=O

InChI Key InChIKey=NSEWXOVGFYEDFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294034   

TargetMultidrug resistance-associated protein 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50294034((R,S)-2-(3,3-Diethylthioureido)-4-methyl-4,5,6,7-t...)
Affinity DataIC50: 4.06E+3nMAssay Description:Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandPNGBDBM50294034((R,S)-2-(3,3-Diethylthioureido)-4-methyl-4,5,6,7-t...)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of BCRP expressed in MCF7 MX cells by Hoechst 33342 stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed