BDBM50293896 CHEMBL552296::N-{5-chloro-4-[2-methyl-4-(2-methyl-2H-pyrazol-3-yl)-quinolin-8-yloxymethyl]-pyridin-3-ylmethyl}-methanesulfonamide

SMILES Cc1cc(-c2ccnn2C)c2cccc(OCc3c(Cl)cncc3CNS(C)(=O)=O)c2n1

InChI Key InChIKey=AMXRUHFKPMZRML-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293896   

TargetB2 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50293896(N-{5-chloro-4-[2-methyl-4-(2-methyl-2H-pyrazol-3-y...)
Affinity DataIC50: 110nMAssay Description:Antagonist activity at B2 receptor in human HF15 cells assessed as inhibition of bradykinin-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50293896(N-{5-chloro-4-[2-methyl-4-(2-methyl-2H-pyrazol-3-y...)
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]bradykinin from human recombinant B2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed