BDBM50289138 3-((E)-2-Pyridin-3-yl-vinyl)-1H-indole::CHEMBL441669

SMILES C(=C/c1cccnc1)\c1c[nH]c2ccccc12

InChI Key InChIKey=XEGNKAULPJNZHP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289138   

TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50289138(3-((E)-2-Pyridin-3-yl-vinyl)-1H-indole | CHEMBL441...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289138(3-((E)-2-Pyridin-3-yl-vinyl)-1H-indole | CHEMBL441...)
Affinity DataKi:  40nMAssay Description:Compound was tested for inhibition of Tryptophan dioxygenase (TDO) from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article