BDBM50273469 CHEMBL4126406

SMILES Cc1oc2ccccc2c1C(=O)c1ccc(OCCC[N+](C)(C)C)cc1

InChI Key InChIKey=VIZAXRZXZDYDFX-UHFFFAOYSA-M

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50273469   

TargetHistone lysine demethylase PHF8(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273469(CHEMBL4126406)
Affinity DataIC50: 1.26E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7B (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase PHF2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273469(CHEMBL4126406)
Affinity DataIC50: 5.98E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7C (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273469(CHEMBL4126406)
Affinity DataIC50: 8.44E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from recombinant His6-tagged human KDM5A (PHD3) (1542 to 1660 residues) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 7A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273469(CHEMBL4126406)
Affinity DataIC50: 5.60E+3nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 7A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273469(CHEMBL4126406)
Affinity DataIC50: 5.60E+3nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2020
Entry Details Article
PubMed
TargetHistone lysine demethylase PHF8(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273469(CHEMBL4126406)
Affinity DataIC50: 3.10E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7B (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2020
Entry Details Article
PubMed