BDBM50269845 CHEMBL4077630

SMILES Oc1ccc(cc1)[C@H]1[C@@H]([C@@H]([C@H]1c1cc(O)cc(=O)o1)c1ccc(O)cc1)c1cc(O)cc(=O)o1

InChI Key InChIKey=RYRAFHXNXUPLCM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50269845   

TargetTyrosyl-DNA phosphodiesterase 1(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50269845(CHEMBL4077630)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Tdp1 (unknown origin) using 5'-(6-TAMN-AGGATCTAAAAGACTT-BHQ-)3' as substrate pretreated for 30 mins followed by substrate addition by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2020
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50269845(CHEMBL4077630)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed