BDBM50267546 (S)-N-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)-7-(2-methoxyethoxy)quinazolin-6-yl)pyrrolidine-2-carboxamide::CHEMBL523122

SMILES COCCOc1cc2ncnc(Nc3c4OCOc4ccc3Cl)c2cc1NC(=O)[C@@H]1CCCN1

InChI Key InChIKey=PXVOZEZXKFLOOY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267546   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50267546((S)-N-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)-7...)
Affinity DataIC50: 89nMAssay Description:Inhibition of Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50267546((S)-N-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)-7...)
Affinity DataIC50: 7.13E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed