BDBM50256713 3-phenyl-2-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triazol-3-yl)piperidin-1-yl)methyl)phenyl)-1,6-naphthyridin-5(6H)-one::CHEMBL262341::CHEMBL507130

SMILES O=c1[nH]ccc2nc(-c3ccc(CN4CCC(CC4)c4nnc([nH]4)-c4ccccn4)cc3)c(cc12)-c1ccccc1

InChI Key InChIKey=BTUWHHFNOHVCMQ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50256713   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256713(CHEMBL507130 | CHEMBL262341 | 3-phenyl-2-(4-((4-(5...)
Affinity DataIC50: 5.61E+3nMAssay Description:Inhibition of human ERG expressed in HEK cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256713(CHEMBL507130 | CHEMBL262341 | 3-phenyl-2-(4-((4-(5...)
Affinity DataIC50: 266nMAssay Description:Inhibition of Akt2 by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256713(CHEMBL507130 | CHEMBL262341 | 3-phenyl-2-(4-((4-(5...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Akt3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256713(CHEMBL507130 | CHEMBL262341 | 3-phenyl-2-(4-((4-(5...)
Affinity DataIC50: 5.61E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256713(CHEMBL507130 | CHEMBL262341 | 3-phenyl-2-(4-((4-(5...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256713(CHEMBL507130 | CHEMBL262341 | 3-phenyl-2-(4-((4-(5...)
Affinity DataIC50: 16nMAssay Description:Inhibition of Akt1 by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256713(CHEMBL507130 | CHEMBL262341 | 3-phenyl-2-(4-((4-(5...)
Affinity DataIC50: 42nMAssay Description:Inhibition of Akt2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed