BDBM50255722 CHEMBL4063885

SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCNC(=S)CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCCCN)[C@@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(O)=O

InChI Key InChIKey=YXKGYVHVWCCQGQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50255722   

TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255722(CHEMBL4063885)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human SIRT5 using H3K9 succinyl peptide as substrate after 5 mins by HPLC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255722(CHEMBL4063885)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of sirtuin 5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255722(CHEMBL4063885)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of SIRT5 (unknown origin) using KQTAR(SuK)STGGKA as substrate in presence of NADMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255722(CHEMBL4063885)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of SIRT5 desuccinylase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255722(CHEMBL4063885)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of GST-tagged SIRT5 (unknown origin) incubated for 10 mins by HPLC based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255722(CHEMBL4063885)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human SIRT5 incubated for 35 mins in presence of NAD by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed