BDBM50255150 CHEMBL521254::N1-{(+/-)-4-[(6-aminopyridin-2-yl)methyl]pyrrolidin-3-yl}-N2,N2-dimethylethane-1,2-diamine tetrachloride

SMILES CN(C)CCN[C@@H]1CNC[C@@H]1Cc1cccc(N)n1

InChI Key InChIKey=YIBXQACZBRNVKO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255150   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255150(N1-{(+/-)-4-[(6-aminopyridin-2-yl)methyl]pyrrolidi...)
Affinity DataKi:  3.33E+3nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255150(N1-{(+/-)-4-[(6-aminopyridin-2-yl)methyl]pyrrolidi...)
Affinity DataKi:  1.40E+5nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255150(N1-{(+/-)-4-[(6-aminopyridin-2-yl)methyl]pyrrolidi...)
Affinity DataKi:  1.95E+5nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed