BDBM50254052 CHEMBL462067::N2-(2,6-dichlorophenyl)-N5,N5-diethyl-N7-(4-(trifluoromethyl)phenyl)thiazolo[5,4-d]pyrimidine-2,5,7-triamine
SMILES CCN(CC)c1nc(Nc2ccc(cc2)C(F)(F)F)c2nc(Nc3c(Cl)cccc3Cl)sc2n1
InChI Key InChIKey=WBHMKZSJKQEZCG-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50254052
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair