BDBM50241443 CHEMBL4092104

SMILES Nc1ccccc1NC(=O)c1ccc(CCn2cc(nn2)-c2cccnc2)cc1

InChI Key InChIKey=YWSALSKBBBBCFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241443   

TargetHistone deacetylase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241443(CHEMBL4092104)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241443(CHEMBL4092104)
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant NAMPT using NAM as substrate preincubated for 5 mins followed by substrate addition measured after 15 mins by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2019
Entry Details Article
PubMed