BDBM50188890 CHEMBL3827794

SMILES COc1cc(cc(OC)c1OC)-c1nc(N2CCOCC2)c2nc(CN(C)c3ncc(cn3)C(=O)NO)n(C)c2n1

InChI Key InChIKey=HHDYRXKUDYTQHA-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50188890   

TargetHistone deacetylase 1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL

LigandBDBM50188890(CHEMBL3827794)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/10/2017
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
West China Hospital of Sichuan University

Curated by ChEMBL

LigandBDBM50188890(CHEMBL3827794)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length recombinant human His-tagged p110 alpha/p85 alpha expressed in baculovirus expression system incubated for 1 hr by kinase-g...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/10/2017
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL