BDBM50187766 7-(4-fluorobenzyl)-9-hydroxy-6,8-dioxo-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-5-yl dimethylcarbamate::CHEMBL212320

SMILES CN(C)C(=O)Oc1c2C(=O)N(Cc3ccc(F)cc3)C(=O)c2c(O)c2ncccc12

InChI Key InChIKey=LECMSGCIFVVUCD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187766   

TargetIntegrase(Human immunodeficiency virus type 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50187766(7-(4-fluorobenzyl)-9-hydroxy-6,8-dioxo-7,8-dihydro...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of strand transfer activity of HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Cyprus

Curated by ChEMBL
LigandPNGBDBM50187766(7-(4-fluorobenzyl)-9-hydroxy-6,8-dioxo-7,8-dihydro...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed