BDBM50184973 CHEMBL3822828

SMILES O=c1nc2\C(CCn2c2ccccc12)=C\N1CCCCC1

InChI Key InChIKey=DFTSYBDNBXZCKJ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50184973   

TargetTranscription activator BRG1(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50184973(CHEMBL3822828)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of His6-tagged human recombinant SMARCA4 bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells after 30 mins using biotinyla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50184973(CHEMBL3822828)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to His6-tagged human recombinant PB1 bromodomain isoform 5 expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by VP-ITC microca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed