BDBM50182299 7-((3-fluoro-5-(1-hydroxy-1-(pyridin-2-yl)propyl)phenoxy)methyl)-4-(furan-3-yl)-2H-chromen-2-one::CHEMBL204633

SMILES CCC(O)(c1cc(F)cc(OCc2ccc3c(cc(=O)oc3c2)-c2ccoc2)c1)c1ccccn1

InChI Key InChIKey=LSZLSTWIIZGABA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50182299   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50182299(7-((3-fluoro-5-(1-hydroxy-1-(pyridin-2-yl)propyl)p...)
Affinity DataIC50: 360nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50182299(7-((3-fluoro-5-(1-hydroxy-1-(pyridin-2-yl)propyl)p...)
Affinity DataIC50: 175nMAssay Description:Inhibition of human 5-LOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50182299(7-((3-fluoro-5-(1-hydroxy-1-(pyridin-2-yl)propyl)p...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed