BDBM50169601 1-Benzenesulfonyl-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indole; oxalic acid::CHEMBL196102::CHEMBL373107

SMILES CN1CCC[C@H]1Cc1cn(c2ccccc12)S(=O)(=O)c1ccccc1

InChI Key InChIKey=ARMHUQQMXHTFEW-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50169601   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169601(CHEMBL196102 | CHEMBL373107 | 1-Benzenesulfonyl-3-...)
Affinity DataIC50: 81.4nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169601(CHEMBL196102 | CHEMBL373107 | 1-Benzenesulfonyl-3-...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169601(CHEMBL196102 | CHEMBL373107 | 1-Benzenesulfonyl-3-...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity against h5-HT6 receptor transiently expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169601(CHEMBL196102 | CHEMBL373107 | 1-Benzenesulfonyl-3-...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed