BDBM50166596 4-(3-(4-(2-methyl-1H-imidazol-1-yl)phenylthio)phenyl)tetrahydro-2H-pyran-4-carboxamide::4-{3-[4-(2-Methyl-imidazol-1-yl)-phenylsulfanyl]-phenyl}-tetrahydro-pyran-4-carboxylic acid amide::CHEMBL195309

SMILES Cc1nccn1-c1ccc(Sc2cccc(c2)C2(CCOCC2)C(N)=O)cc1

InChI Key InChIKey=VPTONMHDLLMOOV-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50166596   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50166596(4-{3-[4-(2-Methyl-imidazol-1-yl)-phenylsulfanyl]-p...)Copy SMILESCopy InChI

Affinity DataIC50: 230nMAssay Description:Inhibition of 5-lipoxygenase mediated LTB4 synthesis in A-23187 simulated human whole bloodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
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