BDBM50162076 CHEMBL3793901

SMILES COc1ccc2nc3[nH]nc(C)c3c(NCCOCCO)c2c1

InChI Key InChIKey=YWEGXZZAORIRQR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50162076   

TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50162076(CHEMBL3793901)
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant human MTH1 expressed in Escherichia coli BL21 DE3 cells preincubated for 15 mins followed by 8-oxo-dGTP substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50162076(CHEMBL3793901)
Affinity DataIC50: 421nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50162076(CHEMBL3793901)
Affinity DataIC50: 410nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed