BDBM50158327 (+/-)isobutyl 2-((4-(diethylamino)phenyl)carbamoyl)-8-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl(methyl)carbamate::CHEMBL181350::[2-(4-Diethylamino-phenylcarbamoyl)-8-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl]-methyl-carbamic acid isobutyl ester

SMILES CCN(CC)c1ccc(NC(=O)C2(CCc3cccc(OC)c3C2)N(C)C(=O)OCC(C)C)cc1

InChI Key InChIKey=KKCWWVHNSBBMSH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50158327   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50158327((+/-)isobutyl 2-((4-(diethylamino)phenyl)carbamoyl...)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of hERG receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50158327((+/-)isobutyl 2-((4-(diethylamino)phenyl)carbamoyl...)
Affinity DataIC50: 16nMAssay Description:Binding affinity to GHSRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50158327((+/-)isobutyl 2-((4-(diethylamino)phenyl)carbamoyl...)
Affinity DataIC50: 29nMAssay Description:Antagonist activity at GHSR expressed in CHOK cells assessed as inhibition of ghrelin-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50158327((+/-)isobutyl 2-((4-(diethylamino)phenyl)carbamoyl...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human GHSR1a receptor assessed as blockade of intracellular Ca2+ mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed