BDBM50153838 1-(3-dimethylaminophenylcarboxamido)-3-(4-isopropoxyphenylcarboxamido)-4-methylbenzene::CHEMBL365472

SMILES CC(C)Oc1ccc(cc1)C(=O)Nc1cc(NC(=O)c2cccc(c2)N(C)C)ccc1C

InChI Key InChIKey=LKYAZIWQMLWADO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50153838   

TargetMitogen-activated protein kinase 14(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153838(1-(3-dimethylaminophenylcarboxamido)-3-(4-isopropo...)
Affinity DataIC50: 170nMAssay Description:Concentration required to inhibit human mitogen activated protein kinase p38 activity More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153838(1-(3-dimethylaminophenylcarboxamido)-3-(4-isopropo...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Smo expressed in mouse NIH/3T3 cells after 20 hrs by Gli reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153838(1-(3-dimethylaminophenylcarboxamido)-3-(4-isopropo...)
Affinity DataIC50: 166nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed