BDBM50146476 CHEMBL99995::N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylidenemethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide

SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(C=C2CCC(CC2)N=O)N(O)C=O)c2ccccc2n1

InChI Key InChIKey=WRJBRPUQVWCVQK-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50146476   

TargetMatrix metalloproteinase-17(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146476(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylidenemeth...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146476(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylidenemeth...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146476(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylidenemeth...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146476(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylidenemeth...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146476(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylidenemeth...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146476(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylidenemeth...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146476(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylidenemeth...)
Affinity DataIC50: 2nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed