BDBM50146213 CHEMBL93207::[7-Hydroxy-4-(4-hydroxy-phenyl)-3,4-dihydro-1H-isoquinolin-2-yl]-phenyl-methanone

SMILES Oc1ccc(cc1)C1CN(Cc2cc(O)ccc12)C(=O)c1ccccc1

InChI Key InChIKey=TXMWYKYJRAYYNL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146213   

TargetEstrogen receptor beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146213([7-Hydroxy-4-(4-hydroxy-phenyl)-3,4-dihydro-1H-iso...)
Affinity DataIC50: 28nMAssay Description:In vitro concentration required to inhibit [3H]estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146213([7-Hydroxy-4-(4-hydroxy-phenyl)-3,4-dihydro-1H-iso...)
Affinity DataIC50: 160nMAssay Description:In vitro concentration required to inhibit [3H]estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed