BDBM50144531 4-((2S,3R)-2-Carboxy-4-oxo-3-piperidin-4-ylmethyl-azetidine-1-carbonyl)-piperazine-1-carboxylic acid 1-isopropyl-2-methyl-propyl ester::CHEMBL72279

SMILES CC(C)C(OC(=O)N1CCN(CC1)C(=O)N1[C@@H]([C@@H](CC2CCNCC2)C1=O)C(O)=O)C(C)C

InChI Key InChIKey=LICYULLQPIZDET-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50144531   

TargetTryptase beta-2/delta/gamma(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144531(4-((2S,3R)-2-Carboxy-4-oxo-3-piperidin-4-ylmethyl-...)
Affinity DataIC50: 29nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144531(4-((2S,3R)-2-Carboxy-4-oxo-3-piperidin-4-ylmethyl-...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibitory activity of compound against Thrombin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144531(4-((2S,3R)-2-Carboxy-4-oxo-3-piperidin-4-ylmethyl-...)
Affinity DataIC50: 6.22E+3nMAssay Description:Inhibitory activity of compound against Plasmin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144531(4-((2S,3R)-2-Carboxy-4-oxo-3-piperidin-4-ylmethyl-...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibitory activity of compound against tissue type plasminogen activator was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144531(4-((2S,3R)-2-Carboxy-4-oxo-3-piperidin-4-ylmethyl-...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory activity of compound against Urokinase-type plasminogen activator was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144531(4-((2S,3R)-2-Carboxy-4-oxo-3-piperidin-4-ylmethyl-...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibitory activity of compound against Coagulation factor X was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144531(4-((2S,3R)-2-Carboxy-4-oxo-3-piperidin-4-ylmethyl-...)
Affinity DataIC50: 935nMAssay Description:Inhibitory activity of compound against Trypsin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed