BDBM50142525 CHEMBL47524::N-(4,5-Dihydro-thiazol-2-yl)-3,4,5-trihydroxy-benzamide

SMILES Oc1cc(cc(O)c1O)C(=O)NC1=NCCS1

InChI Key InChIKey=NTBBUWBAFBYPGL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142525   

TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142525(N-(4,5-Dihydro-thiazol-2-yl)-3,4,5-trihydroxy-benz...)
Affinity DataIC50: 3.44E+4nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed