BDBM50126343 5-[Benzyloxy-(3-methyl-3H-imidazol-4-yl)-methyl]-2''-methyl-biphenyl-2-carbonitrile::5-[Benzyloxy-(3-methyl-3H-imidazol-4-yl)-methyl]-2'-methyl-biphenyl-2-carbonitrile::CHEMBL28937

SMILES Cc1ccccc1-c1cc(ccc1C#N)C(OCc1ccccc1)c1cncn1C

InChI Key InChIKey=WNWCSJWUFYSYRF-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50126343   

LigandPNGBDBM50126343(5-[Benzyloxy-(3-methyl-3H-imidazol-4-yl)-methyl]-2...)
Affinity DataIC50: 84nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126343(5-[Benzyloxy-(3-methyl-3H-imidazol-4-yl)-methyl]-2...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Bovine geranylgeranyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126343(5-[Benzyloxy-(3-methyl-3H-imidazol-4-yl)-methyl]-2...)
Affinity DataEC50:  2.70E+3nMAssay Description:Effective concentration against H-ras processing in NIH 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126343(5-[Benzyloxy-(3-methyl-3H-imidazol-4-yl)-methyl]-2...)
Affinity DataIC50: 65nMAssay Description:In vitro inhibitory activity against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed