BDBM50125228 (S)-2-(2-Bromo-benzoylamino)-3-(1H-indol-3-yl)-propionic acid::CHEMBL268669

SMILES OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)c1ccccc1Br

InChI Key InChIKey=PYLJGABTKOZRCY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50125228   

TargetIntegrin alpha-L/beta-2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50125228((S)-2-(2-Bromo-benzoylamino)-3-(1H-indol-3-yl)-pro...)
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of LFA1/ICAM1 interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50125228((S)-2-(2-Bromo-benzoylamino)-3-(1H-indol-3-yl)-pro...)
Affinity DataIC50: 1.70E+3nMAssay Description:Concentration required to inhibit binding of ICAM-1 to LFA-1 (Leukocyte function-associated antigen-1), evaluated ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
LigandPNGBDBM50125228((S)-2-(2-Bromo-benzoylamino)-3-(1H-indol-3-yl)-pro...)
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibitory activity against association of LFA-1 with intercellular adhesion molecule 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed