BDBM50118802 4-(6-Amino-2-chloro-purin-9-yl)-1-hydroxymethyl-bicyclo[3.1.0]hexane-2,3-diol::CHEMBL337602

SMILES Nc1nc(Cl)nc2n(cnc12)C1C2CC2(CO)C(O)C1O

InChI Key InChIKey=ZPRWMVGQJGNLCO-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50118802   

TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50118802(4-(6-Amino-2-chloro-purin-9-yl)-1-hydroxymethyl-bi...)
Affinity DataEC50:  803nMAssay Description:Effect on forskolin-stimulated cyclic AMP production in intact chinese hamster ovary (CHO) cell expressing the human Adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50118802(4-(6-Amino-2-chloro-purin-9-yl)-1-hydroxymethyl-bi...)
Affinity DataKi:  46nMAssay Description:Binding affinity towards Adenosine A3 receptor (W243 A mutant receptor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50118802(4-(6-Amino-2-chloro-purin-9-yl)-1-hydroxymethyl-bi...)
Affinity DataKi:  83nMAssay Description:Binding affinity towards human Adenosine A3 receptor wild typeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50118802(4-(6-Amino-2-chloro-purin-9-yl)-1-hydroxymethyl-bi...)
Affinity DataKi:  353nMAssay Description:Affinity for human Adenosine A3 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed