BDBM50113286 (1-Hydroxy-1-phosphono-undecyl)-phosphonic acid::1-hydroxyundecane-1,1-diyldiphosphonic acid::CHEMBL298852::undecane-1-hydroxy-1,1-bisphosphonate

SMILES CCCCCCCCCCC(O)(P(O)(O)=O)P(O)(O)=O

InChI Key InChIKey=SXBDBOGSDLDYIY-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50113286   

TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50113286(undecane-1-hydroxy-1,1-bisphosphonate | (1-Hydroxy...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50113286(undecane-1-hydroxy-1,1-bisphosphonate | (1-Hydroxy...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against the human recombinant geranylgeranyl diphosphate synthase (GGPPSase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyprenyl synthetase family protein(Leishmania donovani)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50113286(undecane-1-hydroxy-1,1-bisphosphonate | (1-Hydroxy...)
Affinity DataIC50: 3.42E+3nMAssay Description:Inhibitory activity against Leishmania major Farnesyl diphosphate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50113286(undecane-1-hydroxy-1,1-bisphosphonate | (1-Hydroxy...)
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME (M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50113286(undecane-1-hydroxy-1,1-bisphosphonate | (1-Hydroxy...)
Affinity DataKi:  330nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Leishmania major)
University of British Columbia

Curated by ChEMBL
LigandPNGBDBM50113286(undecane-1-hydroxy-1,1-bisphosphonate | (1-Hydroxy...)
Affinity DataKi:  330nMAssay Description:Inhibition of recombinant Leishmania major FPPS expressed in Escherichia coli BL21(DE3) using GPP and [14C]IPP as substrate incubated for 15 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed