BDBM50100319 CHEMBL3321800

SMILES Cc1ccccc1-n1c(N)c(C(N)=O)c2nc3ccccc3nc12

InChI Key InChIKey=UXTXRVSXYRFEIE-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100319   

TargetEphrin type-B receptor 4(Human)
University of Z£Rich

Curated by ChEMBL

LigandBDBM50100319(CHEMBL3321800)Copy SMILESCopy InChI

Affinity DataIC50: 230nMAssay Description:Inhibition of phosphorylation of full-length myc-tagged human EphB4 overexpressed in mouse embryonic fibroblasts after 90 mins by sandwich ELISAMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/28/2016
Entry Details Article
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TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
Repare Therapeutics

Curated by ChEMBL

LigandBDBM50100319(CHEMBL3321800)Copy SMILESCopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal human recombinant PKMYT1 (76 to 362 residues) expressed in Escherichia coli (DE3) RIL preincubated with compound for 15 mins...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/23/2023
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL