BDBM50099746 CHEMBL51579::N-(9,10-Dioxo-9,10-dihydro-phenanthren-1-yl)-succinamic acid methyl ester

SMILES COC(=O)CCC(=O)Nc1cccc2-c3ccccc3C(=O)C(=O)c12

InChI Key InChIKey=IIEJKCICXMCYNS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50099746   

TargetReceptor-type tyrosine-protein phosphatase C(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099746(N-(9,10-Dioxo-9,10-dihydro-phenanthren-1-yl)-succi...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibitory concentration against CD45 protein-tyrosine phosphatase using lck-10mer as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099746(N-(9,10-Dioxo-9,10-dihydro-phenanthren-1-yl)-succi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against FAP-1 using lck-10 mer as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099746(N-(9,10-Dioxo-9,10-dihydro-phenanthren-1-yl)-succi...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibitory concentration against FAP-1 pNPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099746(N-(9,10-Dioxo-9,10-dihydro-phenanthren-1-yl)-succi...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibitory activity against the cytosolic portion of CD45 protein-tyrosine phosphatase using pNPP as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099746(N-(9,10-Dioxo-9,10-dihydro-phenanthren-1-yl)-succi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed