BDBM50089867 CHEMBL3577626

SMILES Clc1ccc(CCNC(=O)c2ccccc2N2CCC(=O)NC2=O)c(Cl)c1

InChI Key InChIKey=HHQJCXWKFODTFE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50089867   

TargetPoly [ADP-ribose] polymerase 1(Human)
Philochem

Curated by ChEMBL
LigandPNGBDBM50089867(CHEMBL3577626)
Affinity DataIC50: 110nMAssay Description:Inhibition of full length PARP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase activity u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Philochem

Curated by ChEMBL
LigandPNGBDBM50089867(CHEMBL3577626)
Affinity DataIC50: 676nMAssay Description:Inhibition of hexa-histidine tagged recombinant tankyrase 1 biotinylated catalytic domain (amino acids 1106 to 1325) (unknown origin) expressed in Es...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
Philochem

Curated by ChEMBL
LigandPNGBDBM50089867(CHEMBL3577626)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length PARP10 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase activity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Philochem

Curated by ChEMBL
LigandPNGBDBM50089867(CHEMBL3577626)
Affinity DataIC50: 110nMAssay Description:Inhibition of full length PARP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase activity u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Philochem

Curated by ChEMBL
LigandPNGBDBM50089867(CHEMBL3577626)
Affinity DataIC50: 700nMAssay Description:Inhibition of hexa-histidine tagged recombinant tankyrase 1 biotinylated catalytic domain (amino acids 1106 to 1325) (unknown origin) expressed in Es...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed