BDBM50086364 CHEMBL146750::N-Benzyl-3-(3-hydroxy-phenyl)-2,2-dimethyl-3-methylamino-propionamide

SMILES CNC(c1cccc(O)c1)C(C)(C)C(=O)NCc1ccccc1

InChI Key InChIKey=DLVNXVNKPOZNAC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50086364   

TargetKappa-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086364(N-Benzyl-3-(3-hydroxy-phenyl)-2,2-dimethyl-3-methy...)
Affinity DataKi:  5nMAssay Description:Inhibition of [3H]U-69593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086364(N-Benzyl-3-(3-hydroxy-phenyl)-2,2-dimethyl-3-methy...)
Affinity DataKi:  8.70nMAssay Description:Inhibition of [3H]DAMGO binding to rat Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086364(N-Benzyl-3-(3-hydroxy-phenyl)-2,2-dimethyl-3-methy...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]naltrindole binding to human Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed