BDBM50051403 2-((R)-3-(2-Cyano-1H-indol-3-yl)-2-{2-[((2S,6R)-2,6-dimethyl-piperidine-1-carbonyl)-amino]-4-methyl-pentanoylamino}-propionylamino)-hexanoic acid::CHEMBL309003

SMILES CCCCC(NC(=O)[C@@H](Cc1c([nH]c2ccccc12)C#N)NC(=O)C(CC(C)C)NC(=O)N1[C@@H](C)CCC[C@H]1C)C(O)=O

InChI Key InChIKey=SCTZVHRHWDIACG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50051403   

TargetEndothelin-1 receptor(Pig)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50051403(2-((R)-3-(2-Cyano-1H-indol-3-yl)-2-{2-[((2S,6R)-2,...)
Affinity DataIC50: 470nMAssay Description:Binding affinity towards endothelin A receptor in porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetEndothelin receptor type B(Pig)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50051403(2-((R)-3-(2-Cyano-1H-indol-3-yl)-2-{2-[((2S,6R)-2,...)
Affinity DataIC50: 1.60nMAssay Description:Binding affinity towards endothelin B receptor in porcine cerebellum membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed