BDBM50039669 1-[5-Eth-(Z)-ylidene-5H-dibenzo[a,d]cyclohepten-10-yl]-4-methyl-piperazine::CHEMBL90977

SMILES C\C=C1\c2ccccc2C=C(N2CCN(C)CC2)c2ccccc12

InChI Key InChIKey=DISSGPVGANAWAA-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50039669   

Target5-hydroxytryptamine receptor 3A/3B(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50039669(1-[5-Eth-(Z)-ylidene-5H-dibenzo[a,d]cyclohepten-10...)
Affinity DataKi:  35nMAssay Description:Affinity was evaluated by inhibition of [3H]GR-65630 binding to NG108-15 cell transfected with cloned rat 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50039669(1-[5-Eth-(Z)-ylidene-5H-dibenzo[a,d]cyclohepten-10...)
Affinity DataKi:  68nMAssay Description:Affinity was evaluated as inhibition constant for dopamine receptor D1 using [3H]-SCH- 23390 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50039669(1-[5-Eth-(Z)-ylidene-5H-dibenzo[a,d]cyclohepten-10...)
Affinity DataKi:  98nMAssay Description:Affinity was evaluated by inhibition of [125I]LSD binding to NIH 3T3 cells transfected with cloned rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50039669(1-[5-Eth-(Z)-ylidene-5H-dibenzo[a,d]cyclohepten-10...)
Affinity DataKi:  110nMAssay Description:Affinity was evaluated by inhibition of [125I]LSD binding to NIH 3T3 cells transfected with cloned rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50039669(1-[5-Eth-(Z)-ylidene-5H-dibenzo[a,d]cyclohepten-10...)
Affinity DataKi:  300nMAssay Description:Affinity was evaluated by inhibition of [3H]-spiperone binding to COS cells transfected with human dopamine D-4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50039669(1-[5-Eth-(Z)-ylidene-5H-dibenzo[a,d]cyclohepten-10...)
Affinity DataKi:  730nMAssay Description:Affinity was evaluated by inhibition of [3H]spiperone binding to COS cells transfected with human dopamine D-2(long) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed