BDBM50035098 1-(4-Fluoro-phenyl)-3-{4-[3-(4-fluoro-phenyl)-8-aza-bicyclo[3.2.1]oct-2-en-8-yl]-butyl}-1H-indole::CHEMBL62994

SMILES Fc1ccc(cc1)C1=CC2CCC(C1)N2CCCCc1cn(-c2ccc(F)cc2)c2ccccc12

InChI Key InChIKey=NRZHEKZOMMPQDG-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50035098   

TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035098(1-(4-Fluoro-phenyl)-3-{4-[3-(4-fluoro-phenyl)-8-az...)
Affinity DataIC50: 8.00E+3nMAssay Description:Binding affinity towards Dopamine receptor D2 binding site using [3H]spiroperidol.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035098(1-(4-Fluoro-phenyl)-3-{4-[3-(4-fluoro-phenyl)-8-az...)
Affinity DataIC50: 1.20E+3nMAssay Description:Binding affinity towards sigma receptor binding site 1 using [3H](+)-pentazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035098(1-(4-Fluoro-phenyl)-3-{4-[3-(4-fluoro-phenyl)-8-az...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor binding site using [3H]8-OH-DPAT. More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035098(1-(4-Fluoro-phenyl)-3-{4-[3-(4-fluoro-phenyl)-8-az...)
Affinity DataIC50: 3.70E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor binding site using [3H]ketanserin. More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50035098(1-(4-Fluoro-phenyl)-3-{4-[3-(4-fluoro-phenyl)-8-az...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity to sigma-1 opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed