BDBM477355 5-chloro-N-((1S,2R) 2-(6-fluoro-2,3-dimethylphenyl)-1-(5-oxo-4,5-dihydro-::US10889555, Example 114::US11634395, Example 114

SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c(n1)C(=O)N1CCCC1)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C

InChI Key InChIKey=GJQXVCBDQDENLY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 477355   

TargetMuscarinic acetylcholine receptor M1/M2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM477355(US10889555, Example 114 | 5-chloro-N-((1S,2R) 2-(6...)
Affinity DataIC50: 60nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
Go to US Patent

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutial

US Patent
LigandPNGBDBM477355(US10889555, Example 114 | 5-chloro-N-((1S,2R) 2-(6...)
Affinity DataIC50: 60nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
Go to US Patent