BDBM418605 3-methoxy-4-({4-[({6-methyl-2- [methyl(methylsulfonyl)-amino]pyridin- 3-yl}methyl)amino]-5- (trifluoromethyl)pyrirnidin-2- yl}amino)benzamide (49)::US10450297, Example 49

SMILES COc1cc(ccc1Nc1ncc(c(NCc2ccc(C)nc2N(C)S(C)(=O)=O)n1)C(F)(F)F)C(N)=O

InChI Key InChIKey=YTRRXGUBWJKZOA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 418605   

TargetFocal adhesion kinase 1 [410-689](Human)
Pfizer

US Patent
LigandPNGBDBM418605(3-methoxy-4-({4-[({6-methyl-2- [methyl(methylsulfo...)
Affinity DataIC50: 0.590nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
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Date in BDB:
8/31/2020
Entry Details
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