BDBM367610 N-[(1S)-2-[4-[2- (4-Amino-2- chloro-6-methyl- pyrimidin-5-yl) ethyl]-1-piperidyl]-1- methyl-2-oxo-ethyl]-5- methyl-1H-pyrazole- 4-carboxamide::US10227310, Example 2

SMILES C[C@H](NC(=O)c1cn[nH]c1C)C(=O)N1CCC(CCc2c(C)nc(Cl)nc2N)CC1

InChI Key InChIKey=XMPTZLSWBARYOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 367610   

TargetGhrelin O-acyltransferase(Human)
Eli Lilly

US Patent
LigandPNGBDBM367610(US10227310, Example 2 | N-[(1S)-2-[4-[2- (4-Amino-...)
Affinity DataIC50: 54.4nMAssay Description:Prepare test compounds in DMSO to make up a 0.2 mM stock solution. Serially dilute the stock solution in DMSO for ten concentrations with final compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetGhrelin O-acyltransferase(Human)
Eli Lilly

US Patent
LigandPNGBDBM367610(US10227310, Example 2 | N-[(1S)-2-[4-[2- (4-Amino-...)
Affinity DataIC50: 54nMAssay Description:Inhibition of human His-tagged GOAT expressed in baculovirus infected Sf9 cell membrane using desacyl-ghrelin-biotin and octanoyl-CoA as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed